good-or-bad context perturbation perturbation_type cell_line pcid moa +5 adrenal female BIBX-1382 DRUG MCF10A 6918508 EGFR inhibitor +4 adrenal female MG-132 DRUG HELA 462382 proteasome inhibitor +3 adrenal female fenretinide DRUG ASC 5288209 apoptosis stimulant | retinoid receptor agonist +2 adrenal female NSC-3852 DRUG ASC 19103 HDAC inhibitor +1 adrenal female buparlisib DRUG HELA 16654980 PI3K inhibitor -5 adrenal female fulvestrant DRUG MCF7 104741 estrogen receptor antagonist -4 adrenal female canertinib DRUG SKB 156414 EGFR inhibitor -3 adrenal female VANGL2 GENE KO U251MG -2 adrenal female trichostatin-a DRUG NPC 444732 HDAC inhibitor -1 adrenal female N-[(4-methylphenyl)methyl]-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine DRUG NEU 44602352 +5 adrenal male olaparib DRUG NPC 23725625 PARP inhibitor +4 adrenal male entinostat DRUG XC.P908 4261 HDAC inhibitor +3 adrenal male bosutinib DRUG HELA 5328940 Abl kinase inhibitor | Bcr-Abl kinase inhibitor | SRC inhibitor +2 adrenal male TTNPB DRUG THP1 5289501 retinoid receptor agonist +1 adrenal male ivabradine DRUG HA1E 132999 HCN channel blocker | potassium channel blocker | sodium channel blocker -5 adrenal male BAY-61-3606 DRUG A549 10200390 SYK inhibitor -4 adrenal male ASL GENE KO A375 -3 adrenal male lidocaine DRUG A549 3676 histamine receptor agonist -2 adrenal male gestrinone DRUG A549 73707430 progesterone receptor antagonist -1 adrenal male bortezomib DRUG YAPC 387447 NFkB pathway inhibitor | proteasome inhibitor +5 blood-rna female SB-939 DRUG A549 49855250 HDAC inhibitor +4 blood-rna female devazepide DRUG HA1E 443375 CCK receptor antagonist +3 blood-rna female 2-methoxy-N-[(1-methyl-2-benzimidazolyl)methyl]aniline DRUG PC3 42628057 +2 blood-rna female LY-2835219 DRUG MCF10A.PIK3CA.HH 46220502 CDK inhibitor +1 blood-rna female MIF GENE KO ES2 -5 blood-rna female YM-155 DRUG A549 10126189 survivin inhibitor -4 blood-rna female AT-7519 DRUG BT20 11338033 CDK inhibitor -3 blood-rna female salermide DRUG A375 135659046 -2 blood-rna female idarubicin DRUG A549 42890 topoisomerase inhibitor -1 blood-rna female doxorubicin DRUG MCF7 31703 dna polymerase inhibitor | topoisomerase inhibitor +5 blood-rna male RAPGEF6 GENE KO BICR6 +4 blood-rna male ixazomib DRUG XC.P935 25183872 proteasome inhibitor +3 blood-rna male daunorubicin DRUG HT29 30323 RNA synthesis inhibitor | topoisomerase inhibitor +2 blood-rna male PRKRA GENE KO YAPC -5 blood-rna male PKM GENE KO AGS -4 blood-rna male NSDHL GENE KO HT29 -3 blood-rna male PF-03758309 DRUG NEU 25227462 p21 activated kinase inhibitor -2 blood-rna male AT-9283 DRUG A375 135398495 Aurora kinase inhibitor | JAK inhibitor -1 blood-rna male withaferin-a DRUG A549 265237 +5 brown-adipose female ACAN GENE KO BICR6 +4 brown-adipose female PIM1 GENE KO AGS +3 brown-adipose female CSK GENE KO BICR6 +2 brown-adipose female ACSL1 GENE KO A549 +1 brown-adipose female MMP15 GENE KO HT29 -5 brown-adipose female BRD2 GENE KO MCF7 -4 brown-adipose female CYLD GENE KO U251MG -3 brown-adipose female BX-795 DRUG HT29 10077147 IKK inhibitor -2 brown-adipose female HADH GENE KO BICR6 -1 brown-adipose female PDS5A GENE KO ES2 +5 brown-adipose male SF3B1 GENE KO ES2 +4 brown-adipose male parthenolide DRUG HCC515 6473881 NFkB pathway inhibitor +3 brown-adipose male BMS-345541 DRUG SKBR3 9813758 IKK inhibitor +2 brown-adipose male amsacrine DRUG MCF10A 2179 topoisomerase inhibitor +1 brown-adipose male KDM5A GENE KO U251MG -5 brown-adipose male TFRC GENE KO BICR6 -4 brown-adipose male CCNA2 GENE KO KYSE30 -3 brown-adipose male PABPN1 GENE KO AGS +5 colon female alisertib DRUG A549 24771867 Aurora kinase inhibitor +4 colon female AZ-628 DRUG OCILY3 11676786 RAF inhibitor +3 colon female GSK-2110183 DRUG OCILY19 46843057 AKT inhibitor +2 colon female sirolimus DRUG OCILY10 5284616 mTOR inhibitor +1 colon female rosiglitazone DRUG PC3 77999 insulin sensitizer | insulin sensitizer, ppar receptor agonist | PPAR receptor agonist -5 colon female vorinostat DRUG MINO 5311 HDAC inhibitor -4 colon female AFG3L2 GENE KO HT29 -3 colon female MG-132 DRUG MCF7 462382 proteasome inhibitor -2 colon female belinostat DRUG JURKAT 6918638 HDAC inhibitor -1 colon female trichostatin-a DRUG OCILY19 444732 HDAC inhibitor +5 colon male AZ-628 DRUG OCILY3 11676786 RAF inhibitor +4 colon male sirolimus DRUG JURKAT 5284616 mTOR inhibitor +3 colon male sirolimus DRUG HBL1 5284616 mTOR inhibitor +2 colon male geldanamycin DRUG HME1 5288382 HSP inhibitor -5 colon male obatoclax DRUG XC.P905 11404337 BCL inhibitor -4 colon male diltiazem DRUG PC3 39186 calcium channel blocker -3 colon male vorinostat DRUG JURKAT 5311 HDAC inhibitor -2 colon male vorinostat DRUG MINO 5311 HDAC inhibitor -1 colon male thiotepa DRUG HA1E 5453 cytochrome P450 inhibitor +5 cortex female TG-101348 DRUG HA1E 16722836 FLT3 inhibitor | JAK inhibitor +4 cortex female 5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide DRUG LOVO 659101 +3 cortex female I-BET-762 DRUG K562 46943432 bromodomain inhibitor +2 cortex female OTS-167 DRUG SKL.C 135398499 maternal embryonic leucine zipper kinase inhibitor +1 cortex female tivozanib DRUG HA1E 9911830 VEGFR inhibitor -5 cortex female tacedinaline DRUG NPC.215 2746 HDAC inhibitor -4 cortex female BRCA2 GENE KO MCF7 -3 cortex female lawsone DRUG HA1E 10125107 +5 cortex male IKK-16 DRUG K562 9549298 IKK inhibitor +4 cortex male XL-888 DRUG HEK293 57748689 +3 cortex male SLC2A4RG GENE KO PC3 +2 cortex male 4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1-triazolecarboxamide DRUG VCAP 50904528 +1 cortex male KW-2478 DRUG XC.P931 23116322 HSP inhibitor -5 cortex male SERPINA6 GENE KO ES2 -4 cortex male OGT GENE KO MCF7 -3 cortex male sirolimus DRUG P1A82 5284616 mTOR inhibitor -2 cortex male RRM1 GENE KO MCF7 +5 gastrocnemius female THZ-2-98-01 DRUG HA1E 73707613 +4 gastrocnemius female sorafenib DRUG HA1E 216239 FLT3 inhibitor | KIT inhibitor | PDGFR tyrosine kinase receptor inhibitor | RAF inhibitor | RET tyrosine kinase inhibitor | VEGFR inhibitor +3 gastrocnemius female berbamine DRUG A375 275182 -5 gastrocnemius female gemcitabine DRUG PC3 60750 ribonucleotide reductase inhibitor -4 gastrocnemius female entinostat DRUG A549 4261 HDAC inhibitor -3 gastrocnemius female withaferin-a DRUG HT29 265237 -2 gastrocnemius female N-[4-[[[6-(3,5-dimethyl-4-isoxazolyl)-4-quinazolinyl]amino]methyl]phenyl]acetamide DRUG A375 17757086 +5 gastrocnemius male PF-03758309 DRUG THP1 25227462 p21 activated kinase inhibitor +4 gastrocnemius male 1-[(8S,9S,10R)-10-(hydroxymethyl)-9-[4-(4-methoxyphenyl)phenyl]-1,6-diazabicyclo[6.2.0]decan-6-yl]-2-pyridin-4-ylethanone DRUG HT29 54666615 +3 gastrocnemius male ACVR1C GENE KO MCF7 +2 gastrocnemius male AMG-232 DRUG A375 58573469 MDM inhibitor +1 gastrocnemius male verrucarin-a DRUG 1HAE 5369716 -5 gastrocnemius male JNJ-7706621 DRUG ASC 5330790 CDK inhibitor -4 gastrocnemius male duloxetine DRUG MCF7 60835 norepinephrine reuptake inhibitor | serotonin–norepinephrine reuptake inhibitor (SNRI) -3 gastrocnemius male lopinavir DRUG HT29 92727 HIV protease inhibitor -2 gastrocnemius male vinblastine DRUG HCC515 13342 microtubule inhibitor | tubulin polymerization inhibitor -1 gastrocnemius male idelalisib DRUG BJAB 11625818 PI3K inhibitor +5 heart female PD-0325901 DRUG SKL 9826528 MEK inhibitor +4 heart female 16beta-Bromoandrosterone DRUG HA1E 16219061 +3 heart female EMF-sumo1-39 DRUG A375 51003694 +2 heart female CHEK1 GENE KO PC3 +1 heart female PRKACG GENE KO BICR6 -5 heart female N-(2-aminophenyl)-N'-[(2R,3R)-2-[[(4-chlorophenyl)sulfonyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]heptanediamide DRUG MCF7 44506579 -4 heart female tozasertib DRUG HA1E 5494449 Aurora kinase inhibitor | Bcr-Abl kinase inhibitor | FLT3 inhibitor | JAK inhibitor -3 heart female NDUFS6 GENE KO PC3 -2 heart female levamisole DRUG YAPC 26879 acetylcholine receptor agonist +5 heart male 1-[(3R,9R,10S)-9-[[cyclohexylmethyl(methyl)amino]methyl]-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-3-naphthalen-1-ylurea DRUG A375 54616374 +4 heart male CP-724714 DRUG BT20 9874913 EGFR inhibitor | protein tyrosine kinase inhibitor +3 heart male alisertib DRUG A375 24771867 Aurora kinase inhibitor +2 heart male MG-132 DRUG PC3 462382 proteasome inhibitor +1 heart male homoharringtonine DRUG HT29 285033 protein synthesis inhibitor -5 heart male gemcitabine DRUG HT29 60750 ribonucleotide reductase inhibitor -4 heart male (3S,3'S,4'R,5'S)-5'-(2-hydroxyethyl)-5-iodo-4'-[(4-methoxyphenyl)-dimethylsilyl]-3'-methyl-1-prop-2-enyl-2-spiro[indole-3,2'-oxolane]one DRUG HA1E 24869062 -3 heart male tamoxifen DRUG HA1E 2733526 estrogen receptor antagonist | selective estrogen receptor modulator (SERM) -2 heart male brefeldin-a DRUG OV7 5287620 protein synthesis inhibitor -1 heart male 8-(2-Hydroxy-3-methoxy-3-methylbutyl)-7-methoxy-1-benzopyran-2-one DRUG HA1E 23757203 +5 hippocampus female CCNA2 GENE KO BICR6 +4 hippocampus female clofarabine DRUG HT29 119182 ribonucleotide reductase inhibitor +3 hippocampus female CD226 GENE KO YAPC +2 hippocampus female CCNA2 GENE KO BICR6 +1 hippocampus female TYMS GENE KO PC3 -5 hippocampus female azacitidine DRUG HUVEC.A 9444 DNA methyltransferase inhibitor -4 hippocampus female maxacalcitol DRUG MCF10A.KRAS.HG 66577028 vitamin D receptor agonist -3 hippocampus female NPC26 DRUG HA1E 3465537 -2 hippocampus female HG-5-113-01 DRUG HT29 25226483 -1 hippocampus female KMT2B GENE KO U251MG +5 hippocampus male LY-294002 DRUG HT29 3973 DNA dependent protein kinase inhibitor | mTOR inhibitor | phosphodiesterase inhibitor | PI3K inhibitor | PLK inhibitor +4 hippocampus male SLC2A5 GENE KO MCF7 +3 hippocampus male atorvastatin DRUG MDAMB231 60823 HMGCR inhibitor +2 hippocampus male UNC-669 DRUG NPC.CAS9 46931242 L3MBTL antagonist +1 hippocampus male everolimus DRUG MCF7 6442177 mTOR inhibitor -5 hippocampus male TRIM46 GENE KO MCF7 -4 hippocampus male CHEK1 GENE KO U251MG -3 hippocampus male bortezomib DRUG HA1E 387447 NFkB pathway inhibitor | proteasome inhibitor -2 hippocampus male CAM-9-027-3 DRUG XC.L10 49849912 -1 hippocampus male epirubicin DRUG HELA 41867 topoisomerase inhibitor +5 hypothalamus female wortmannin DRUG VCAP 3003565 PI3K inhibitor +4 hypothalamus female PD-0325901 DRUG XC.P931 9826528 MEK inhibitor +3 hypothalamus female selumetinib DRUG XC.P911 10127622 MEK inhibitor +2 hypothalamus female trametinib DRUG XC.P931 11707110 MEK inhibitor +1 hypothalamus female entinostat DRUG NPC.179 4261 HDAC inhibitor -5 hypothalamus female HTR1F GENE KO A549 -4 hypothalamus female ethoprop DRUG MCF7 3289 -3 hypothalamus female nilotinib DRUG HA1E 644241 Abl kinase inhibitor | Bcr-Abl kinase inhibitor -2 hypothalamus female ARFGEF2 GENE KO AGS -1 hypothalamus female crizotinib DRUG XC.P906 11626560 ALK tyrosine kinase receptor inhibitor +5 hypothalamus male ifosfamide DRUG HT29 3690 DNA alkylating agent +4 hypothalamus male dolastatin-10 DRUG YAPC 9810929 tubulin polymerization inhibitor +3 hypothalamus male clozapine DRUG NPC.8330 135398737 dopamine receptor antagonist | serotonin receptor antagonist +2 hypothalamus male cucurbitacin-i DRUG HEPG2 44483311 -5 hypothalamus male fluoxetine DRUG NPC.179 3386 selective serotonin reuptake inhibitor (SSRI) -4 hypothalamus male BIX-01294 DRUG NPC.179 25150857 histone lysine methyltransferase inhibitor -3 hypothalamus male flunarizine DRUG NPC.179 941361 calcium channel blocker -2 hypothalamus male saracatinib DRUG HEK293 10302451 SRC inhibitor -1 hypothalamus male C-646 DRUG HUVEC.A 1285940 +5 kidney female ALDH5A1 GENE KO U251MG +4 kidney female resminostat DRUG THP1 11609955 HDAC inhibitor +3 kidney female AMY2B GENE KO A375 +2 kidney female N-(2-methoxyphenyl)-N-[(3-oxo-1-benzothiophen-2-ylidene)amino]acetamide DRUG HEPG2 759940 +1 kidney female AZD-8330 DRUG A549 16666708 MEK inhibitor -5 kidney female bruceantin DRUG HT29 5281304 protein synthesis inhibitor -4 kidney female withaferin-a DRUG VCAP 265237 -3 kidney female bortezomib DRUG MCF10A 387447 NFkB pathway inhibitor | proteasome inhibitor -2 kidney female digoxin DRUG XC.P911 2724385 ATPase inhibitor +5 kidney male spiramide DRUG PHH 68186 +4 kidney male ST-4062971 DRUG VCAP 49835860 +3 kidney male benzoxiquine DRUG HCC515 6855 antiinfective drug +2 kidney male CCNA2 GENE KO ES2 +1 kidney male KIN001-043 DRUG MCF7 24906282 -5 kidney male GPR22 GENE KO HT29 -4 kidney male MG-132 DRUG A549 462382 proteasome inhibitor -3 kidney male barasertib-HQPA DRUG HCC515 16007391 Aurora kinase inhibitor -2 kidney male vardenafil DRUG PC3 110634 phosphodiesterase inhibitor -1 kidney male PPP2CA GENE KO YAPC +5 liver female obatoclax DRUG MCF7 11404337 BCL inhibitor +4 liver female clomifene DRUG HUVEC.A 1548953 estrogen receptor antagonist +3 liver female bortezomib DRUG XC.R10 387447 NFkB pathway inhibitor | proteasome inhibitor +2 liver female 2-(dimethylamino)-1-[(8R,9S,10R)-10-(hydroxymethyl)-9-[4-[(E)-2-phenylethenyl]phenyl]-1,6-diazabicyclo[6.2.0]decan-6-yl]ethanone DRUG HA1E 54666678 +1 liver female VU-0413238-1 DRUG VCAP 44907115 -5 liver female GW-843682X DRUG HEPG2 9826308 PLK inhibitor -4 liver female 6-(1,3-benzodioxol-5-yl)-N-methyl-N-[(2-methyl-4-thiazolyl)methyl]-4-quinazolinamine DRUG HEPG2 44223970 -3 liver female mitomycin-c DRUG XC.P033 5702003 DNA alkylating agent | DNA synthesis inhibitor -2 liver female volasertib DRUG A375 10461508 PLK inhibitor -1 liver female PLEKHM1 GENE KO ES2 +5 liver male crizotinib DRUG SKMEL5 11626560 ALK tyrosine kinase receptor inhibitor +4 liver male vorinostat DRUG A375 5311 HDAC inhibitor +3 liver male salmeterol DRUG VCAP 5152 adrenergic receptor agonist +2 liver male trifluoperazine DRUG PC3 5566 dopamine receptor antagonist +1 liver male ponatinib DRUG XC.P932 24826799 Bcr-Abl kinase inhibitor | FLT3 inhibitor | PDGFR tyrosine kinase receptor inhibitor -5 liver male CCNA2 GENE KO A549 -4 liver male CC-930 DRUG PC3 11597537 JNK inhibitor -3 liver male NVP-BGJ398 DRUG NPC.CAS9 53235510 FGFR inhibitor -2 liver male nilotinib DRUG HA1E 644241 Abl kinase inhibitor | Bcr-Abl kinase inhibitor +5 lung female sirolimus DRUG HCT116.TP53.HR 5284616 mTOR inhibitor +4 lung female belinostat DRUG HELA 6918638 HDAC inhibitor +3 lung female BUB1 GENE KO A375 +2 lung female VX-745 DRUG HEK293 3038525 p38 MAPK inhibitor +1 lung female tanespimycin DRUG A549 6505803 HSP inhibitor -5 lung female clioquinol DRUG HT29 2788 chelating agent -4 lung female saracatinib DRUG HME1 10302451 SRC inhibitor -3 lung female (2S,3S,4R)-3-[4-(2-cyclohexylethynyl)phenyl]-4-(hydroxymethyl)-2-azetidinecarbonitrile DRUG A549 54650164 -2 lung female vismodegib DRUG HA1E 24776445 hedgehog pathway inhibitor | smoothened receptor antagonist -1 lung female gefitinib DRUG LNCAP 123631 EGFR inhibitor +5 lung male mercaptopurine DRUG PC3 667490 immunosuppressant | protein synthesis inhibitor | purine antagonist +4 lung male belinostat DRUG MCF7 6918638 HDAC inhibitor +3 lung male 3-[(3aS,10bS)-2-[4-(3-hydroxypropoxy)phenyl]-4-oxo-5-prop-2-enyl-6,10b-dihydrooxazolo[4,5-d][2]benzazepin-3a-yl]propanoic acid tert-butyl ester DRUG MCF7 24868580 +2 lung male KU-0060648 DRUG HA1E 11964036 -5 lung male fludroxycortide DRUG PC3 15209 glucocorticoid receptor agonist -4 lung male BAY-61-3606 DRUG NEU 10200390 SYK inhibitor -3 lung male CTNNB1 GENE KO A549 -2 lung male clomethiazole DRUG MCF10A 10783 GABA receptor antagonist | GABA receptor modulator +5 ovaries female estradiol DRUG HELA 5757 estrogen receptor agonist +4 ovaries female chrysin DRUG HELA 5281607 breast cancer resistance protein inhibitor +3 ovaries female norgestrel DRUG HELA 29985980 progesterone receptor agonist +2 ovaries female zardaverine DRUG HELA 5723 phosphodiesterase inhibitor +1 ovaries female genistein DRUG HELA 5280961 tyrosine kinase inhibitor -5 ovaries female MLN-2480 DRUG A375 25161177 RAF inhibitor -4 ovaries female wortmannin DRUG THP1 3003565 PI3K inhibitor -3 ovaries female PD-0325901 DRUG A375 9826528 MEK inhibitor -2 ovaries female cobimetinib DRUG HT29 16222096 MEK inhibitor -1 ovaries female cobimetinib DRUG HT29 16222096 MEK inhibitor +5 small-intestine female COPA GENE KO SNU761 +4 small-intestine female PF-03758309 DRUG MCF10A 25227462 p21 activated kinase inhibitor +3 small-intestine female medroxyprogesterone DRUG VCAP 10631 progesterone receptor agonist +2 small-intestine female licochalcone-a DRUG XC.L10 3923 topoisomerase inhibitor +1 small-intestine female trichostatin-a DRUG A375 444732 HDAC inhibitor -5 small-intestine female PI-103 DRUG XC.P908 9884685 mTOR inhibitor | PI3K inhibitor -4 small-intestine female ER-27319 DRUG MCF7 9799509 mediator release inhibitor | SYK inhibitor -3 small-intestine female TAK-715 DRUG BT20 9952773 p38 MAPK inhibitor -2 small-intestine female withaferin-a DRUG HEPG2 265237 +5 small-intestine male ZSTK-474 DRUG BT20 11647372 PI3K inhibitor +4 small-intestine male KU-0060648 DRUG HA1E 11964036 +3 small-intestine male CVF-SUMO-11 DRUG MCF7 51003716 +2 small-intestine male podophyllotoxin DRUG THP1 10607 microtubule inhibitor | tubulin polymerization inhibitor +1 small-intestine male IKK-2-inhibitor-V DRUG HCC515 5081913 IKK inhibitor | NFkB pathway inhibitor -5 small-intestine male mitoxantrone DRUG TMD8 4212 topoisomerase inhibitor -4 small-intestine male BMS-387032 DRUG MDAMB231 3025986 CDK inhibitor | cell cycle inhibitor | MCL1 inhibitor -3 small-intestine male rasagiline DRUG JURKAT 3052776 monoamine oxidase inhibitor -2 small-intestine male withaferin-a DRUG HEPG2 265237 +5 spleen female cobimetinib DRUG K562 16222096 MEK inhibitor +4 spleen female ixazomib DRUG HT29 25183872 proteasome inhibitor +3 spleen female 2-Amino-4-(4-chlorophenyl)-1-(4-methylphenyl)-6-oxopyridine-3,5-dicarbonitrile DRUG VCAP 1034641 +2 spleen female nocodazole DRUG XC.P905 4122 tubulin polymerization inhibitor -5 spleen female rifabutin DRUG HA1E 5482874 protein synthesis inhibitor -4 spleen female alsterpaullone DRUG HT29 5005498 -3 spleen female trichostatin-a DRUG HEPG2 444732 HDAC inhibitor -2 spleen female 2-(dimethylamino)-1-[(8R,9S,10S)-10-(hydroxymethyl)-9-[4-[(E)-2-phenylethenyl]phenyl]-1,6-diazabicyclo[6.2.0]decan-6-yl]ethanone DRUG A375 54666677 -1 spleen female 5-nonyloxytryptamine DRUG HT29 1797 +5 spleen male MLN-8054 DRUG HELA 11712649 Aurora kinase inhibitor +4 spleen male amikacin DRUG YAPC 37768 bacterial 30S ribosomal subunit inhibitor +3 spleen male vorinostat DRUG XC.R10 5311 HDAC inhibitor +2 spleen male pyocyanin DRUG MCF10A.WT.HP -5 spleen male deoxycholic-acid DRUG MCF7 222528 biliverdin reductase A activator | G protein-coupled receptor agonist -4 spleen male equol DRUG MCF7 91469 estrogen receptor agonist -3 spleen male A-443654 DRUG THP1 10172943 -2 spleen male panobinostat DRUG HT29 6918837 HDAC inhibitor -1 spleen male 5-nonyloxytryptamine DRUG HT29 1797 +5 testes male (3S)-2-[(S)-tert-butylsulfinyl]-3-(2-hydroxyethyl)-4-[3-(3-methoxyphenyl)phenyl]-N-(2,2,2-trifluoroethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide DRUG PC3 54649454 +4 testes male lopinavir DRUG A549 92727 HIV protease inhibitor +3 testes male MG-132 DRUG HA1E 462382 proteasome inhibitor +2 testes male WZ-7043 DRUG HELA 73265276 +1 testes male torin-2 DRUG HA1E 51358113 mTOR inhibitor -5 testes male epoxycholesterol DRUG A549 3247059 -4 testes male simvastatin DRUG PC3 54454 HMGCR inhibitor -3 testes male dexamethasone DRUG A549 5743 glucocorticoid receptor agonist -2 testes male 3-[(4-Chloroanilino)methylidene]-2-(2-hydroxyethylimino)-9-methyl-4-pyrido[1,2-a]pyrimidinone DRUG PC3 3241836 -1 testes male calcitriol DRUG HELA 5280453 vitamin D receptor agonist +5 vastus-lateralis female diminazene-aceturate DRUG YAPC 2354 angiotensin converting enzyme activator +4 vastus-lateralis female MAP2K3 GENE KO HS944T +3 vastus-lateralis female sonidegib DRUG A549 24775005 smoothened receptor antagonist +2 vastus-lateralis female DBH GENE KO MCF7 +1 vastus-lateralis female SA-247615 DRUG VCAP 44507291 -5 vastus-lateralis female SR-33805 DRUG YAPC 9850876 calcium channel blocker -4 vastus-lateralis female hexachlorophene DRUG HEPG2 3598 potassium channel activator -3 vastus-lateralis female phorbol-myristate-acetate DRUG MDAMB231 27924 PKC activator -2 vastus-lateralis female palbociclib DRUG XC.P930 5330286 CDK inhibitor -1 vastus-lateralis female mitoxantrone DRUG A375 4212 topoisomerase inhibitor +5 vastus-lateralis male bortezomib DRUG XC.L10 387447 NFkB pathway inhibitor | proteasome inhibitor +4 vastus-lateralis male D-4476 DRUG HA1E 6419753 TGF beta receptor inhibitor +3 vastus-lateralis male MLN-8054 DRUG SHSY5Y 11712649 Aurora kinase inhibitor +2 vastus-lateralis male rigosertib DRUG SHSY5Y 6918736 cell cycle inhibitor | PLK inhibitor +1 vastus-lateralis male GSK-461364 DRUG SKBR3 15983966 PLK inhibitor -5 vastus-lateralis male PF-477736 DRUG BT20 135565545 CHK inhibitor -4 vastus-lateralis male mocetinostat DRUG HELA 9865515 HDAC inhibitor -3 vastus-lateralis male entinostat DRUG HELA 4261 HDAC inhibitor -2 vastus-lateralis male entinostat DRUG NPC.170 4261 HDAC inhibitor -1 vastus-lateralis male KCNMA1 GENE KO PC3 +5 vena-cava female romidepsin DRUG MCF10A 5352062 HDAC inhibitor +4 vena-cava female gefitinib DRUG XC.P930 123631 EGFR inhibitor +3 vena-cava female trichostatin-a DRUG MCF10A.KRAS.HG 444732 HDAC inhibitor +2 vena-cava female bortezomib DRUG MCF7 387447 NFkB pathway inhibitor | proteasome inhibitor +1 vena-cava female panobinostat DRUG XC.P905 6918837 HDAC inhibitor -5 vena-cava female oncrasin-1 DRUG XC.P912 872445 apoptosis stimulant -4 vena-cava female sirolimus DRUG TMD8 5284616 mTOR inhibitor -3 vena-cava female KU-0063794 DRUG XC.P905 16736978 mTOR inhibitor -2 vena-cava female PF-05212384 DRUG MINO 44516953 mTOR inhibitor | PI3K inhibitor +5 vena-cava male MNITMT DRUG A375 364622 lymphocyte inhibitor +4 vena-cava male trimethobenzamide DRUG HELA 5577 histamine receptor antagonist +3 vena-cava male HAL GENE KO ES2 +2 vena-cava male AKR1C4 GENE KO ES2 +1 vena-cava male triamcinolone DRUG HELA 31307 glucocorticoid receptor agonist -5 vena-cava male SIN3A GENE KO A375 -4 vena-cava male ABT-737 DRUG XC.P931 11228183 BCL inhibitor -3 vena-cava male UK-356618 DRUG PC3 10370504 metalloproteinase inhibitor -2 vena-cava male CCND3 GENE KO BICR6 -1 vena-cava male GPX3 GENE KO A375 +5 white-adipose female AKR1C4 GENE KO ES2 +4 white-adipose female VX-765 DRUG HA1E 59772309 caspase inhibitor +3 white-adipose female withaferin-a DRUG MCF7 265237 +2 white-adipose female hydroflumethiazide DRUG MDAMB231 3647 sodium/potassium/chloride transporter inhibitor +1 white-adipose female IL18BP GENE KO HT29 -5 white-adipose female WDR87 GENE KO AGS -4 white-adipose female wortmannin DRUG THP1 3003565 PI3K inhibitor -3 white-adipose female CD86 GENE KO PC3 -2 white-adipose female CELA2A GENE KO A375 -1 white-adipose female ABCA7 GENE KO U251MG +5 white-adipose male PUS7 GENE KO ES2 +4 white-adipose male NFE2L3 GENE KO U251MG +3 white-adipose male 2-Amino-1-(4-methylphenyl)-6-oxo-4-phenylpyridine-3,5-dicarbonitrile DRUG MCF7 824820 +2 white-adipose male STBD1 GENE KO BICR6 +1 white-adipose male 1-(4-fluorophenyl)-3-[(3S,9R,10R)-12-[(2R)-1-hydroxypropan-2-yl]-9-[[(4-methoxyphenyl)methyl-methylamino]methyl]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]urea DRUG MCF7 46903887 -5 white-adipose male BEST1 GENE KO YAPC -4 white-adipose male N-(3,4-dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide DRUG MCF7 4547230 -3 white-adipose male PMF1-BGLAP GENE KO U251MG -2 white-adipose male tibolone DRUG MCF7 444008 androgen receptor agonist | estrogen receptor agonist | progesterone receptor agonist -1 white-adipose male AKR1C4 GENE KO ES2